Population
Rabbit skeletal muscle myosin and clam adductor paramyosin
Comparison
Rapid coprecipitation to form cofilaments vs Slowly formed cofilaments and homofilaments
Design
Preclinical
Authors
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May support paramyosin as an invertebrate muscle relaxant; leaves open any role in vertebrate cardiac regulation.
Paramyosin may serve as part of a relaxing mechanism within invertebrate muscles by competitively inhibiting actin-activated myosin ATPase when rapidly coprecipitated.
Epstein et al. (1975) studied this question.
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