Key result
Acute non-left anterior descending acute coronary syndrome can act as a physical trigger for Takotsubo syndrome in patients with coexistent coronary artery disease.
Why the study?
Coexistent coronary artery disease presents diagnostic dilemmas in patients with Takotsubo syndrome.
Case Report (n=2)
Highlights that acute non-LAD acute coronary syndrome can serve as a physical trigger for Takotsubo syndrome, complicating diagnosis.
May prompt TTS consideration in non-LAD ACS with CAD; leaves open need for prospective validation before practice change.
Cardiomyopathy of Takotsubo syndrome (TS) is typically triggered by an emotional stress in postmenopausal women. Coexistent coronary artery disease presents diagnostic dilemmas in patients with TS, as seen in the 2 cases presented. In the first case, acute coronary syndrome acts as a physical trigger for TS when a middle-aged man presents with an inferior myocardial infarct, and in the second case, coronary artery disease is a bystander when an elderly woman develops TS after a fall and facial trauma. The novel teaching point is that acute non-left anterior descending acute coronary syndrome could trigger TS.
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Girgis et al. (2019) conducted a case report in Takotsubo syndrome and coexistent coronary artery disease (n=2). Acute non-left anterior descending acute coronary syndrome was evaluated. Acute non-left anterior descending acute coronary syndrome can act as a physical trigger for Takotsubo syndrome in patients with coexistent coronary artery disease.
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