Key result
Age > 65 years did not significantly influence long-term mortality in patients with Takotsubo syndrome compared to those ≤ 65 years (HR 1.0, p=0.60).
Why the study?
Does age > 65 years compared to ≤ 65 years affect short- and long-term outcomes in patients with Takotsubo syndrome?
Cohort (n=114)
No
Does age > 65 years compared to ≤ 65 years affect short- and long-term outcomes in patients with Takotsubo syndrome?
Hazard Ratio: 1 (95% CI 0.9–1)
Absolute Event Rate: 30.3% vs 27.1%
p-value: p=0.60
Age does not independently predict long-term mortality in Takotsubo syndrome, though older patients have a higher incidence of heart failure and younger patients have more life-threatening arrhythmias.
Does not support age-based long-term mortality prognostication in Takotsubo syndrome; leaves open differential HF and arrhythmia risks by age.
BACKGROUND: Takotsubo syndrome (TS) is an important cardiac disease that affects predominantly postmenopausal women. This study was conducted to determine the impact of age on the short- and long-term outcome of TS patients. METHODS & CONCLUSIONS: Age does not influence the clinical course of TS in terms of the short- as well as long-term outcome. The study revealed a higher incidence of life threatening arrhythmias in the younger patient age-group and a higher incidence of heart failure among the older group of patients.
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Huseynov et al. (2017) conducted a cohort in Takotsubo syndrome (n=114). Age > 65 years vs. Age ≤ 65 years was evaluated on Long-term mortality (HR 1.0, 95% CI 0.9-1.0, p=0.60). Age > 65 years did not significantly influence long-term mortality in patients with Takotsubo syndrome compared to those ≤ 65 years (HR 1.0, p=0.60).
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