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November 5, 2018Clinical CardiologyOpen Access

Male gender in patients with Takotsubo syndrome was associated with a significantly higher probability of in-hospital mortality compared to female gender (3.7% vs 1.1%; P<0.001).

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Why the study?

Does male gender affect in-hospital outcomes in patients admitted with Takotsubo syndrome?

Population

39,662 admissions with Takotsubo syndrome between 2006 and 2014, 91.7% female, mean age 66.5 and 61.6.

Comparison

Male gender vs Female gender

Design

Cohort

Follow-up

In-hospital

Key result

Male gender in patients with Takotsubo syndrome was associated with a significantly higher probability of in-hospital mortality compared to female gender (3.7% vs 1.1%; P<0.001).

Authors

ALAlejandro LemorARAlvaro J. Ramos‐RodriguezRVRicardo De La Villa

Discussion

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Member takes

Overview

Gender may influence TTS hospital outcomes; hypothesis-generating and should not yet change practice.

Study Design

Type

Observational (n=39,662)

Multicenter

Yes

Structured PICO

Does male gender affect in-hospital outcomes in patients admitted with Takotsubo syndrome?

P
Population
39,662 patients admitted with Takotsubo syndrome between 2006 and 2014, evaluated for gender differences in in-hospital outcomes.
E
Exposure
Male gender
C
Comparator
Female gender
O
Outcome
In-hospital mortalityhard clinical

Main Result

Absolute Event Rate: 3.7% vs 1.1%

p-value: p=<0.001

Although Takotsubo syndrome is predominantly seen in females, male patients experience significantly higher in-hospital morbidity and mortality.

Cite This Study

Lemor et al. (2018) conducted an observational in Takotsubo syndrome (n=39,662). Male gender vs. Female gender was evaluated on In-hospital mortality (p=<0.001). Male gender in patients with Takotsubo syndrome was associated with a significantly higher probability of in-hospital mortality compared to female gender (3.7% vs 1.1%; P<0.001).

synapsesocial.com/papers/6a6caaa1f44fa9f079db5584https://doi.org/10.1002/clc.23109
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