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April 24, 2022BiologyOpen Access

Male gender in Takotsubo Syndrome is associated with higher rates of severe in-hospital complications, fatal arrhythmias, and mortality compared to females.

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Why the study?

Most patients with Takotsubo Syndrome (TTS) are postmenopausal females, making TTS in males rare, and gender differences have not been sufficiently investigated.

What are the gender differences in the presentation, complications, and mechanisms of Takotsubo Syndrome?

Population

Patients with TTS

Comparison

Males vs females with TTS

Key result

Male gender in Takotsubo Syndrome is associated with higher rates of severe in-hospital complications, fatal arrhythmias, and mortality compared to females.

Authors

TMTsutomu MurakamiTKTomoyoshi KomiyamaHKHiroyuki Kobayashi

Discussion

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Member takes

Overview

Males with TTS may need more HF respiratory support; Level 5 data leaves open gender-specific risk stratification.

Structured PICO

What are the gender differences in the presentation, complications, and mechanisms of Takotsubo Syndrome?

P
Population
Patients with Takotsubo Syndrome (TTS)
E
Exposure
Male gender (as an exposure/risk factor)
C
Comparator
Female gender
O
Outcome
Gender differences in clinical presentation, complications, and mechanisms

Males with Takotsubo Syndrome experience more severe acute complications and higher in-hospital mortality than females, necessitating more careful observation and intervention.

Cite This Study

Murakami et al. (2022) conducted a review in Takotsubo Syndrome. Male gender vs. Female gender was evaluated. Male gender in Takotsubo Syndrome is associated with higher rates of severe in-hospital complications, fatal arrhythmias, and mortality compared to females.

synapsesocial.com/papers/6a6caaa1f44fa9f079db5578https://doi.org/10.3390/biology11050653
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