Key result
Male sex was not significantly associated with in-hospital mortality (OR 1.31) or 5-year mortality (HR 1.66) compared to female sex in patients with cardiogenic shock complicating Takotsubo syndrome.
Why the study?
Sex-related differences in Takotsubo syndrome have been described, but information has been lacking in patients who develop cardiogenic shock.
Does male sex affect mortality in patients with cardiogenic shock complicating Takotsubo syndrome?
Population
412 patients with Takotsubo syndrome with cardiogenic shock
Comparison
Men vs women
Design
Cohort study
Follow-up
5 years
Authors
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Similar mortality despite worse male features in Takotsubo cardiogenic shock; leaves open whether sex-specific risk stratification is needed.
Observational (n=412)
Yes
Does male sex affect mortality in patients with cardiogenic shock complicating Takotsubo syndrome?
Odds Ratio: 1.31 (95% CI 0.64–2.68)
Absolute Event Rate: 16.9% vs 12.6%
p-value: p=0.468
Despite worse baseline characteristics and higher rates of complications in men, short- and long-term mortality rates in cardiogenic shock complicating Takotsubo syndrome are similar between men and women.
Tomasino et al. (2024) conducted an observational in Cardiogenic shock complicating Takotsubo syndrome (n=412). Male sex vs. Female sex was evaluated on In-hospital mortality (OR 1.31, 95% CI 0.64-2.68, p=0.468). Male sex was not significantly associated with in-hospital mortality (OR 1.31) or 5-year mortality (HR 1.66) compared to female sex in patients with cardiogenic shock complicating Takotsubo syndrome.
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