Key result
The Dor procedure increased average ejection fraction from 29% to 39% and achieved an 18-month overall survival rate of 89% in patients with end-stage ischemic heart failure.
Why the study?
Does the Dor procedure improve ejection fraction and survival in patients with end-stage ischemic heart failure?
Does the Dor procedure improve ejection fraction and survival in patients with end-stage ischemic heart failure?
The Dor procedure improves ejection fraction and demonstrates favorable survival in end-stage ischemic heart failure, with echocardiography playing a critical role in surgical evaluation.
May support Dor procedure in end-stage ischemic HF; leaves open need for randomized confirmation.
The Dor procedure, or infarction excision surgery, was first used in 1984. It is a surgical treatment option for patients with end-stage ischemic heart failure. In a recently published multicenter study that included a total of 439 patients, average ejection fraction increased from 29 +/- 10% to 39 +/- 12% after surgery. In our experience, the overall survival rate 18 months after surgery is 89%, and the preoperative mortality rate is 6.6%. These results are similar to the previous reports from Dor's group, which confirmed the certain value of the surgery. Echocardiography, including intraoperative transesophageal echocardiography, plays an important role in clarifying cardiac anatomies, absolute left ventricular (LV) volumes, ejection fraction, and mitral regurgitation in patients with ischemic heart failure undergoing this surgery. With the development of ultrasound and computer technology, three-dimensional echocardiography may be preferred when evaluating the surgical results, including determination of absolute LV volumes. Communication between experienced cardiac surgeons and echocardiographers in the operating room is essential for successful outcomes and reliable evaluation of the surgery.
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Shiota et al. (2002) conducted a review in end-stage ischemic heart failure (n=439). Dor procedure (infarction excision surgery) vs. Baseline was evaluated on ejection fraction. The Dor procedure increased average ejection fraction from 29% to 39% and achieved an 18-month overall survival rate of 89% in patients with end-stage ischemic heart failure.
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