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August 1, 1992Acta Anaesthesiologica Scandinavica

Haemodynamic changes during spinal anaesthesia with slow continuous infusion or single dose of plain bupivacaine

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Why the study?

Does continuous spinal anaesthesia with bupivacaine improve haemodynamic stability compared to single-dose spinal anaesthesia in elderly patients undergoing orthopaedic surgery?

Population

40 elderly patients scheduled for orthopaedic surgery of the hip or knee

Comparison

Continuous spinal anaesthesia with plain 0.5%… vs Single-dose spinal anaesthesia with 3 ml of…

Design

Cohort

Follow-up

during surgery

Authors

MPMikko PitkänenInvalidisäätiöPRPer H. RosenbergUniversity of Applied Sciences WedelMSM. SilvantoUniversity of Turku

Discussion

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Implication

Similar haemodynamic changes observed with both techniques; hypothesis-generating and should not yet change practice.

Structured PICO

Does continuous spinal anaesthesia with bupivacaine improve haemodynamic stability compared to single-dose spinal anaesthesia in elderly patients undergoing orthopaedic surgery?

P
Population
40 elderly patients scheduled for orthopaedic surgery of the hip or knee
I
Intervention
Continuous spinal anaesthesia with plain 0.5% bupivacaine (bolus of 1.0 ml or 0.5 ml, followed by infusion at 2 ml/h)
C
Comparator
Single-dose spinal anaesthesia with 3 ml of plain 0.5% bupivacaine
O
Outcome
Haemodynamic changes (central venous pressure, arterial pressures, need for sympathomimetic medication) and spread of analgesiasurrogate

Titration of bupivacaine for continuous spinal anaesthesia causes minor haemodynamic changes that are similar to those seen with single-dose spinal bupivacaine.

Cite This Study

Pitkänen et al. (1992) studied this question.

synapsesocial.com/papers/6a86ec893f44447e627cb843https://doi.org/10.1111/j.1399-6576.1992.tb03512.x
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Surgical Repair of Hip Fractures Using Continuous Spinal Anesthesia1989 · 21 citations
  2. 2Comparison of continuous spinal and continuous epidural anaesthesia for lower limb surgery in elderly patients A retrospective study1989 · 96 citations
  3. 3Technical problems associated with the use of 32‐gauge and 22‐gauge spinal catheters1992 · 29 citations
  4. 4A Comparison of the Hydrochloride and Carbon Dioxide Salts of Lidocaine and Prilocaine in Epidural Analgesia1965 · 684 citations