Key result
Intravenous epinephrine (5 microg) produced an initial increase in systemic vascular resistance to 129% of control followed by a reduction to 57%, and increased cardiac output to 152% of control.
Why the study?
Does a small intravenous bolus of epinephrine alter cardiac output and systemic vascular resistance in cardiac surgical patients?
Does a small intravenous bolus of epinephrine alter cardiac output and systemic vascular resistance in cardiac surgical patients?
Small bolus doses of intravenous epinephrine in cardiac surgical patients cause a biphasic response in systemic vascular resistance, ultimately leading to a significant reduction that may induce hypotension.
No takes yet. Share an insight, caveat, or question.
May warrant caution for hypotension risk with low-dose epinephrine boluses in cardiac surgery; hypothesis-generating case observation needing confirmation.
Linton et al. (2005) studied Cardiac surgery (n=10). Intravenous epinephrine vs. Baseline was evaluated on Changes in cardiac output and systemic vascular resistance. Intravenous epinephrine (5 microg) produced an initial increase in systemic vascular resistance to 129% of control followed by a reduction to 57%, and increased cardiac output to 152% of control.
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