February 1, 2002Anesthesia & Analgesia

The Impact of Postoperative Atrial Fibrillation on Neurocognitive Outcome After Coronary Artery Bypass Graft Surgery

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Why the study?

Does postoperative atrial fibrillation worsen cognitive function in patients undergoing elective coronary artery bypass graft surgery?

Population

411 patients undergoing elective coronary artery bypass graft surgery

Comparison

Postoperative atrial fibrillation (exposure) vs No postoperative atrial fibrillation

Design

Cohort

Follow-up

6 weeks

Authors

TSTimothy StanleyUniversity of Ulster GMG. Burkhard MackensenUniversity of Washington HGHilary P. GrocottCardiac Surgery

Discussion

Member takes

Implication

Postoperative AF was associated with greater cognitive decline after CABG; hypothesis-generating and requires prospective confirmation before changing practice.

Structured PICO

Does postoperative atrial fibrillation worsen cognitive function in patients undergoing elective coronary artery bypass graft surgery?

Population

411 patients undergoing elective coronary artery bypass graft surgery (308 completed both pre- and postoperative testing)

Intervention

Postoperative atrial fibrillation (exposure)

Comparator

No postoperative atrial fibrillation

Outcome

Change in cognitive function measured by a composite cognitive index (mean of four domain scores) at 6 weeks after surgery

Postoperative atrial fibrillation is associated with significant neurocognitive decline 6 weeks after elective CABG surgery.

Cite This Study

Stanley et al. (2002) studied this question.

synapsesocial.com/papers/6a86ef76cbc6304817bef49b https://doi.org/10.1213/00000539-200202000-00011

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Implication

Postoperative AF was associated with greater cognitive decline after CABG; hypothesis-generating and requires prospective confirmation before changing practice.