Why the study?
Does isometric muscle contraction evoke renal vasoconstriction and decrease renal blood flow via reflex increase in renal sympathetic nerve activity in cats?
Population
8 chloralose-anesthetized cats
Comparison
1-min isometric contraction of the hindlimb… vs Baseline state, renal denervation, cutting L4-S1…
Design
Preclinical
Authors
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Supports reflex renal vasoconstriction via sympathetic activation in cats; leaves open translation to human exercise hemodynamics.
Does isometric muscle contraction evoke renal vasoconstriction and decrease renal blood flow via reflex increase in renal sympathetic nerve activity in cats?
Reflex stimulation of renal sympathetic nerve activity from contracting muscle induces renal vasoconstriction and decreases renal blood flow in a feline model.
Matsukawa et al. (1992) studied this question.
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