Key result
Elevated TRV/TVI (OR 99; 95% CI 4.865-2015) and TRV/AcT (OR 12.68; 95% CI 1.163-379.3) ratios significantly predicted the development of pulmonary artery hypertension at 12 months.
Why the study?
Do echocardiographic parameters (TRV/TVI and TRV/AcT ratios) predict the development of pulmonary artery hypertension in patients with systemic sclerosis?
Cohort (n=38)
Do echocardiographic parameters (TRV/TVI and TRV/AcT ratios) predict the development of pulmonary artery hypertension in patients with systemic sclerosis?
Odds Ratio: 99 (95% CI 4.865–2015)
p-value: p=0.004
Echocardiographic ratios TRV/TVI and TRV/AcT are strong predictors of future pulmonary artery hypertension development in patients with systemic sclerosis.
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May support risk stratification in systemic sclerosis; hypothesis-generating and requires prospective validation before guiding practice.
Frea et al. (2011) conducted a cohort in Systemic sclerosis (n=38). Elevated TRV/TVI and TRV/AcT ratios was evaluated on Development of pulmonary artery hypertension (PAH) (OR 99, 95% CI 4.865-2015, p=0.004). Elevated TRV/TVI (OR 99; 95% CI 4.865-2015) and TRV/AcT (OR 12.68; 95% CI 1.163-379.3) ratios significantly predicted the development of pulmonary artery hypertension at 12 months.
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