Tertiary and secondary alkoxycyanohydrins such as 1 and 2 can be synthesized in high diasteromeric purity. Alkoxyacyl cyanides are allowed to react with allylsilanes or alkoxyaldehydes with silyl cyanides, namely in the presence of chelating reagents such as TiCl4, SnCl4, or Znl2.
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Reetz et al. (1985) studied this question.
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