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February 9, 2022Frontiers in Clinical Diabetes and HealthcareOpen Access

This review provides updated guidance on the management of diabetic ketoacidosis and hyperglycemic hyperosmolar state, emphasizing appropriate fluid resuscitation, insulin therapy, and electrolyte monitoring.

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Why the study?

Diabetic ketoacidosis and hyperglycemic hyperosmolar state represent common and challenging clinical management in practice, motivating an updated review of management and a suggested practical pathway.

Design

Review article

Key result

This review provides updated guidance on the management of diabetic ketoacidosis and hyperglycemic hyperosmolar state, emphasizing appropriate fluid resuscitation, insulin therapy, and electrolyte monitoring.

Authors

MAMohammed AldhaeefiNANamareq AldardeerNANada Alkhani

Discussion

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Overview

Requires heightened vigilance for HHS given its mortality; leaves open optimal protocol refinements pending prospective trials.

Structured PICO

P
Population
Patients with hyperglycemic crisis, specifically diabetic ketoacidosis (DKA) and hyperglycemic hyperosmolar state (HHS).
I
Intervention
Clinical management including fluid resuscitation, insulin therapy, and electrolyte replacement.

This review summarizes the pathophysiology, diagnosis, and updated management pathways for diabetic ketoacidosis and hyperglycemic hyperosmolar state based on recent guidelines.

Cite This Study

Aldhaeefi et al. (2022) conducted a review in Hyperglycemic Crisis (Diabetic Ketoacidosis and Hyperglycemic Hyperosmolar State). Management of Hyperglycemic Crisis (Fluids, Insulin, Electrolytes) was evaluated. This review provides updated guidance on the management of diabetic ketoacidosis and hyperglycemic hyperosmolar state, emphasizing appropriate fluid resuscitation, insulin therapy, and electrolyte monitoring.

synapsesocial.com/papers/6a86fd5dd08104c969cb9df6https://doi.org/10.3389/fcdhc.2021.820728
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Hyperglycemic Crisis: Diabetic Ketoacidosis and Hyperglycemic Hyperosmolar State2024 · 2 citations
  2. 2Severe Hyperglycemic Crisis: A Presentation of Diabetic Ketoacidosis Requiring Intubation2026
  3. 3Clinical profiles, Outcomes and Risk Factors among Type 2 Diabetic Inpatients with Diabetic Ketoacidosis and Hyperglycemic Hyperosmolar State: A Hospital-Based Analysis over a 6-Year Period2020 · 2 citations
  4. 4Clinical profiles, Outcomes and Risk Factors among Type 2 Diabetic Inpatients with Diabetic Ketoacidosis and Hyperglycemic Hyperosmolar State: A Hospital-Based Analysis over a 6-Year Period2020 · 1 citations
  5. 5Clinical profile and outcomes of adult patients with hyperglycemic emergencies managed at a tertiary care hospital in Nigeria2012 · 27 citations