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January 1, 2012Nigerian Medical JournalOpen Access

Clinical profile and outcomes of adult patients with hyperglycemic emergencies managed at a tertiary care hospital in Nigeria

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Key result

Among adult Nigerian patients presenting with hyperglycemic emergencies, 55.2% had no prior diabetes diagnosis, common precipitants were non-compliance and infections, and the mortality rate was 3.6%.

Population

84 adult patients with diabetic ketoacidosis and hyperosmolar hyperglycemic state admitted to a tertiary…

Design

Cohort

Follow-up

mean 18.85 days (duration of hospital stay)

Authors

AEAndrewE Edo

Discussion

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Overview

Hyperglycemic emergencies often reveal undiagnosed diabetes in Nigerian adults; leaves open whether targeted screening improves outcomes.

Study Design

Type

Observational (n=84)

Multicenter

No

Structured PICO

P
Population
84 adult patients with hyperglycemic emergencies (DKA and HHS) managed at a tertiary care hospital in Nigeria, with a mean age of 50.6 years and 59.5% female.
E
Exposure
Standard management protocol for DKA and HHS including intravenous fluids, insulin, and potassium replacement
O
Outcome
Clinical profile, precipitating factors, and treatment outcomes (mortality and duration of hospital stay)hard clinical

Hyperglycemic emergencies in Nigeria frequently present as the first manifestation of diabetes, predominantly in T2DM patients, with infections and non-compliance as major precipitants and a low mortality rate under standard care.

Limitations

  • Retrospective study design relying on hospital records
  • Single-center study at a tertiary care hospital, which may not represent the general population
  • Exclusion of patients with grossly incomplete data
  • Small sample size of 84 patients

Cite This Study

AndrewE Edo (2012) conducted an observational in Hyperglycemic emergencies (Diabetic ketoacidosis and hyperosmolar hyperglycemic state) (n=84). Hyperglycemic emergencies (DKA and HHS) was evaluated on Mortality rate. Among adult Nigerian patients presenting with hyperglycemic emergencies, 55.2% had no prior diabetes diagnosis, common precipitants were non-compliance and infections, and the mortality rate was 3.6%.

synapsesocial.com/papers/6a8acc1e95f0361a9ebe93fdhttps://doi.org/10.4103/0300-1652.104378
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Clinical profiles, Outcomes and Risk Factors among Type 2 Diabetic Inpatients with Diabetic Ketoacidosis and Hyperglycemic Hyperosmolar State: A Hospital-Based Analysis over a 6-Year Period2020 · 2 citations
  2. 2Clinical profiles, Outcomes and Risk Factors among Type 2 Diabetic Inpatients with Diabetic Ketoacidosis and Hyperglycemic Hyperosmolar State: A Hospital-Based Analysis over a 6-Year Period2020 · 1 citations
  3. 3Clinical profile of patients with diabetic ketoacidosis and hyperglycemic hyperosmolar syndrome in Japan: A multicenter retrospective cohort study2023
  4. 4Clinical Profile, Precipitating Factors, and In-Hospital Outcomes of Patients with Diabetic Ketoacidosis: A Prospective Study from a Tertiary Care Center in North India2026
  5. 5Clinical Characteristics and Outcome of Hyperglycaemic Emergencies in Johannesburg Africans1997 · 41 citations