Population
Patients with obesity and noninsulin-dependent diabetes mellitus (NIDDM)
Design
Review
Authors
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Should not alter hypertension management in obesity or NIDDM; hypothesis-generating for insulin-mediated sympathetic pathways.
This review highlights the hypothesis that hyperinsulinemia and insulin resistance drive hypertension in obesity and NIDDM via sympathetic stimulation and renal sodium reabsorption.
Daly et al. (1991) studied this question.