Key result
Direct oral anticoagulant therapy during dental extractions did not increase bleeding outcomes, with 0 bleeding events observed in the DOAC group and similar dental bleeding scores to the VKA group.
Why the study?
Quantitative assessment of bleeding in dental extractions is rarely reported, and assessing bleeding might provide evidence to predict and minimize postoperative outcomes.
Do direct oral anticoagulants (DOACs) increase bleeding outcomes in individuals undergoing dental extractions compared to vitamin K antagonists or no anticoagulation?
Cohort (n=45)
Do direct oral anticoagulants (DOACs) increase bleeding outcomes in individuals undergoing dental extractions compared to vitamin K antagonists or no anticoagulation?
DOAC therapy does not appear to increase bleeding risk during dental extractions compared to VKAs or no anticoagulation.
May aid bleeding risk assessment during DOAC extractions; leaves open whether quantification predicts complications or alters management.
BACKGROUND: Quantitative assessment of bleeding in dental extractions is rarely reported in the literature. The assessment of bleeding might provide additional evidence to predict and minimize postoperative outcomes. The aim of this study was to evaluate the pattern of bleeding in individuals taking direct oral anticoagulants (DOACs) submitted to dental extractions. METHODS: Intraoperative bleeding was evaluated by using total collected bleeding corrected by absorbance reading (dental bleeding score). To monitoring bleeding episodes from the day of surgery, this cohort was followed up until the seventh postoperative day. RESULTS: Forty-five procedures were performed in three comparative groups, patients under DOACs, individuals taking vitamin K antagonists (VKAs) and without anticoagulant therapy. No bleeding events were observed in procedures carried out in individuals of the DOAC group. Additional hemostatic measures were required in two procedures in the VKA group and one in the non-anticoagulated group. The dental bleeding scores obtained for the DOAC and VKA groups were similar. CONCLUSIONS: Our data suggest that the DOAC therapy did not result in increased bleeding outcomes in this sample.
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Rocha et al. (2021) conducted a cohort in dental extractions (n=45). Direct oral anticoagulants (DOACs) vs. Vitamin K antagonists (VKAs) and no anticoagulant therapy was evaluated on Intraoperative bleeding (dental bleeding score) and bleeding episodes. Direct oral anticoagulant therapy during dental extractions did not increase bleeding outcomes, with 0 bleeding events observed in the DOAC group and similar dental bleeding scores to the VKA group.
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