Key result
Large conductance, calcium- and voltage-activated K+ (BK) channels are uniquely characterized by their dual regulation by both cytosolic Ca2+ and membrane voltage.
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BK channel dual regulation guides vascular tone models; leaves open targeted cardiovascular therapies.
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Christopher J. Lingle (2007) studied this question. Large conductance, calcium- and voltage-activated K+ (BK) channels are uniquely characterized by their dual regulation by both cytosolic Ca2+ and membrane voltage.
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