Key result
Large conductance calcium-activated K+ (BK) channels exhibit a large single-channel conductance of approximately 300 pS and are widely distributed in many different tissues.
Key points are not available for this paper at this time.
BK channel properties support mechanistic cardiovascular research; leaves open targeted therapeutic exploration in disease.
Large conductance calcium-activated K+ channels, also referred to as “BK” or “maxi K” channels because of their big single-channel conductance (∼300 pS in symmetrical 150 mM KCl) are widely distributed in many different tissues ([Latorre 1994][1]; [Kaczorowski et al. 1996][2]). A signature
No takes yet. Share an insight, caveat, or question.
Karl L. Magleby (2001) studied this question. Large conductance calcium-activated K+ (BK) channels exhibit a large single-channel conductance of approximately 300 pS and are widely distributed in many different tissues.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: