Why the study?
Does intravenous diltiazem improve left ventricular isovolumic relaxation time in patients with hypertrophic cardiomyopathy?
Population
11 patients with hypertrophic obstructive and non-obstructive cardiomyopathy
Comparison
Intravenous injection of diltiazem vs Baseline (pre-injection)
Design
Case_series
Follow-up
5 to 10 minutes
Authors
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May improve diastolic relaxation in HCM; hypothesis-generating and should not yet change practice.
Does intravenous diltiazem improve left ventricular isovolumic relaxation time in patients with hypertrophic cardiomyopathy?
Intravenous diltiazem significantly shortens prolonged left ventricular isovolumic relaxation time in patients with hypertrophic cardiomyopathy, suggesting an improvement in diastolic function.
Nagao et al. (1983) studied this question.
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