February 1, 1994British Journal of Radiology
Lung metastasectomy in patients with soft tissue sarcoma
Why the study?
Does pulmonary metastasectomy improve survival in patients with soft tissue sarcoma and isolated lung metastases?
Population
189 patients with soft tissue sarcoma who developed lung metastases as the sole first site of disseminated…
Comparison
Pulmonary metastasectomy vs No surgery
Design
Cohort
Follow-up
5 years
Authors
Discussion
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Member takes
Implication
May support metastasectomy in selected patients; leaves open whether benefit reflects selection bias or true effect.
Structured PICO
Does pulmonary metastasectomy improve survival in patients with soft tissue sarcoma and isolated lung metastases?
P
Population
189 patients with soft tissue sarcoma who developed lung metastases as the sole first site of disseminated disease between 1970 and 1990 at the Royal Marsden Hospital Sarcoma Unit.
I
Intervention
Pulmonary metastasectomy (thoracotomy/lung resection)
C
Comparator
No surgery
O
Outcome
Overall 5-year survival and subsequent survival from the time lung metastases developedhard clinical
Pulmonary metastasectomy is associated with significantly improved survival in selected patients with soft tissue sarcoma and isolated lung metastases.
Limitations
- lack of prospective data
- lack of a randomized trial
Cite This Study
Robinson et al. (1994) studied this question.