Key result
The apoB/apoA-I ratio was the strongest independent predictor of severe coronary artery disease (Gensini score ≥ 47) in patients with type 2 diabetes, with an odds ratio of 5.67.
Why the study?
Do lipid and lipoprotein ratios predict the severity of new-onset coronary artery disease in patients with type 2 diabetes mellitus?
Population
380 consecutive patients with type 2 diabetes mellitus and new on-set coronary artery disease, mean age…
Design
Cross-sectional
Authors
Loading...
May aid CAD severity assessment in T2DM; hypothesis-generating and should not yet change practice.
Cross-Sectional (n=380)
No
Do lipid and lipoprotein ratios predict the severity of new-onset coronary artery disease in patients with type 2 diabetes mellitus?
Odds Ratio: 5.67 (95% CI 1.45–23.92)
p-value: p=0.003
The apoB/apoA-I ratio is a strong independent predictor of coronary artery disease severity, as assessed by the Gensini score, in patients with type 2 diabetes mellitus and new-onset CAD.
Du et al. (2016) conducted a cross-sectional in New on-set coronary artery disease complicated with type 2 diabetes mellitus (n=380). Apolipoprotein B to apolipoprotein A-I ratio (apoB/apoA-I) vs. Lower apoB/apoA-I ratio or other lipid ratios was evaluated on High Gensini score (≥ 47 points) indicating severe coronary artery disease (OR 5.67, 95% CI 1.45-23.92, p=0.003). The apoB/apoA-I ratio was the strongest independent predictor of severe coronary artery disease (Gensini score ≥ 47) in patients with type 2 diabetes, with an odds ratio of 5.67.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: