The J-curve Association between Systolic Blood Pressure and Clinical Outcomes in Ischemic Stroke or TIA: The BOSS Study

Figures

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  Figure 1. Patient Flow Chart. BOSS indicates Blood Pressure and Clinical Outcome in TIA or Ischemic Stroke; SMBP, self-measured blood pressure.

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  Figure 2. Adjusted Hazard Ratios among SBP Categories for Cumulative Incidence of Outcomes within 90 Days. HR indicates hazard ratio; CI, confidence interval. Adjusted hazard ratios were estimated with adjustment for age, gender, medical history (hypertension, diabetes mellitus, and dyslipidemia), atrial fibrillation, admission NHISS score, and secondary prevention (anti-platelet, anti-lipid, and anti-hypertension).

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  Figure 3. Continuous Hazard Ratios for Clinical Outcomes within 90 Days and 1 Year. Continuous hazard ratios and 95% confidence intervals for CVE (A), stroke recurrence (B) within 90 days, and CVE (C), stroke recurrence (D) at 1 year. A test on the relationship between the clinical outcome and SBP levels gave a significant result for nonlinearity (A) P < 0.0001, (B) P < 0.0001, (C) P = 0.0032, D: P = 0.0007).

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  Figure 4. Adjusted Hazard Ratios among SBP Categories for Cumulative Incidence of Outcomes at 1 Year. HR indicates hazard ratio; CI, confidence interval. Adjusted hazard ratios were estimated with adjustment for age, gender, medical history (hypertension, diabetes mellitus, and dyslipidemia), atrial fibrillation, admission NHISS score, and secondary prevention (anti-platelet, anti-lipid, and anti-hypertension).