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April 1, 1999Journal of Applied Physiology

Chronic exposure to nicotine alters endothelium-dependent arteriolar dilatation: effect of superoxide dismutase

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Authors

WMWilliam G. MayhanUniversity of Nebraska at Omaha GSGlenda M. SharpeLaboratoire d’immunologie intégrative du cancer

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Implication

Chronic nicotine may impair endothelium-dependent dilatation; hypothesis-generating for human vascular risk, needs confirmation.

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Cite This Study

Mayhan et al. (1999) studied this question.

synapsesocial.com/papers/6a8718a25ee22a1e35cbabfa https://doi.org/10.1152/jappl.1999.86.4.1126

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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

1Smoking Impairs the Activity of Endothelial Nitric Oxide Synthase in Saphenous Vein1996 · 155 citations
2Apparent tolerance to the acute effect of nicotine results in part from distribution kinetics.1987 · 91 citations
3Responses of cerebral arterioles to adenosine 5'-diphosphate, serotonin, and the thromboxane analogue U-46619 during chronic hypertension.1988 · 101 citations
4Cigarette smoke extract attenuates endothelium-dependent arteriolar dilatation in vivo1991 · 37 citations