Why the study?
Does the chronicity of atrial fibrillation affect the duration of sinus rhythm after transthoracic cardioversion in dogs with naturally occurring AF?
Does the chronicity of atrial fibrillation affect the duration of sinus rhythm after transthoracic cardioversion in dogs with naturally occurring AF?
In dogs with spontaneous atrial fibrillation, a longer duration of documented AF and the presence of structural heart disease are associated with a shorter duration of sinus rhythm maintenance after successful transthoracic cardioversion.
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Longer AF duration and structural heart disease were associated with shorter sinus rhythm maintenance after cardioversion in dogs; hypothesis-generating and requires prospective confirmation.
BACKGROUND: Atrial fibrillation (AF) in dogs can be managed by electrical cardioversion to sinus rhythm, but early recurrence of AF occurs in some dogs. In humans, the commonly evaluated clinical variables for prediction of early relapse of AF are left atrial size and duration of AF. It is unclear whether the duration of AF affects maintenance of sinus rhythm after cardioversion in dogs with spontaneous AF. HYPOTHESIS: That duration of sinus rhythm after cardioversion is related to the chronicity of AF. ANIMALS: Forty-one consecutive dogs that had undergone successful transthoracic cardioversion for spontaneous AF were evaluated. METHODS: The relationship between the duration of documented AF and the duration of sinus rhythm after cardioversion was statistically evaluated using data obtained retrospectively. The effects of structural heart disease and pretreatment with amiodarone were also evaluated. RESULTS: The presence of structural heart disease and the duration of documented AF had significant effects on maintenance of sinus rhythm after cardioversion (P <.001 and P=.022, respectively). The duration of documented AF was inversely related to the duration of sinus rhythm (P=.022) in dogs with and without structural heart disease. CONCLUSIONS AND CLINICAL IMPORTANCE: Estimates of duration of sinus rhythm based on the duration of documented AF are provided for dogs with and without heart disease allowing prediction of risk for early AF relapse.
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Bright et al. (2008) studied this question.
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