Why the study?
Heparin-induced thrombocytopenia is a severe prothrombotic drug reaction that makes anticoagulation during cardiopulmonary bypass highly challenging.
This review summarizes perioperative strategies for managing cardiopulmonary bypass in cardiac surgery patients with heparin-induced thrombocytopenia.
Multidisciplinary HIT management in cardiac surgery requires caution; leaves open optimal CPB protocols for prospective validation.
Heparin-induced thrombocytopenia (HIT) is a severe, immune-mediated, adverse drug reaction that paradoxically induces a prothrombotic state. Particularly in the setting of cardiac surgery, where full anticoagulation is required during cardiopulmonary bypass, the management of HIT can be highly challenging, and requires a multidisciplinary approach. In this short review, the different perioperative strategies to run cardiopulmonary bypass will be summarized.
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Ranta et al. (2021) studied this question.
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