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February 25, 2016Scientific ReportsOpen Access

Universal structures of normal and pathological heart rate variability

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Population

Healthy subjects and patients with pathological conditions

Design

Other

Authors

AGAlfonso M. Gañán‐CalvoUniversidad de SevillaJFJuan Fajardo-LópezClinica Santa Maria

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Overview

May offer quantitative HRV assessment of health-pathology gradient; leaves open prospective clinical validation before practice change.

Structured PICO

P
Population
Healthy subjects and patients with pathological conditions (myocardial infarction, heart failure, and recovery from sudden death)
I
Intervention
Generalized N-dimensional normalized graph representing heart rate variability
O
Outcome
Identification of universal arrhythmic patterns as signatures of health and pathologysurrogate

A novel N-dimensional graph of heart rate variability can quantitatively distinguish between healthy cardiac adaptability and pathological states like heart failure or myocardial infarction.

Cite This Study

Gañán‐Calvo et al. (2016) studied this question.

synapsesocial.com/papers/6a879b2bc70d2262fca29d73https://doi.org/10.1038/srep21749
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