April 1, 2000Genes & DevelopmentOpen Access

Ribosome shunting in the cauliflower mosaic virus 35S RNA leader is a special case of reinitiation of translation functioning in plant and animal systems

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Population

Wheat germ extract (WGE) and rabbit reticulocyte lysate (RRL) in vitro translation systems

Design

Preclinical

Authors

LRLyubov A. RyabovaInstitut de Biologie Moléculaire des Plantes THThomas HöhnKarlsruhe Institute of Technology

Discussion

Member takes

Implication

Clarifies termination requirement for viral shunting; leaves open conservation in mammalian translation systems.

Structured PICO

Population

Wheat germ extract (WGE) and rabbit reticulocyte lysate (RRL) in vitro translation systems

Intervention

Study of ribosomal shunt mechanism using cauliflower mosaic virus (CaMV) 35S RNA leader and downstream ORF VII

Outcome

Mechanism of ribosomal shunt and reinitiation of translation

Ribosomal shunting in the CaMV 35S RNA leader functions as a special case of translation reinitiation requiring proper termination at a preceding small ORF.

Cite This Study

Ryabova et al. (2000) studied this question.

synapsesocial.com/papers/6a87a3227bacf6711cf300fc https://doi.org/10.1101/gad.14.7.817

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Ribosome shunting in the cauliflower mosaic virus 35S RNA leader is a special case of reinitiation of translation functioning in plant and animal systems

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Ribosome shunting in the cauliflower mosaic virus 35S RNA leader is a special case of reinitiation of translation functioning in plant and animal systems

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider