The Syndrome of Sarcoidosis, Psoriasis, and Gout

Clinical Staff Conference1 December 1962The Syndrome of Sarcoidosis, Psoriasis, and GoutCombined Clinical Staff Conference at the National Institutes of HealthJOSEPH J. BUNIM, M.D., F.A.C.P., DANIEL V. KIMBERG, M.D., LOUIS B. THOMAS, M.D., EUGENE J. VAN SCOTT, M.D., GERALD KLATSKIN, M.D., F.A.C.P.JOSEPH J. BUNIM, M.D., F.A.C.P.Search for more papers by this author, DANIEL V. KIMBERG, M.D.Search for more papers by this author, LOUIS B. THOMAS, M.D.Search for more papers by this author, EUGENE J. VAN SCOTT, M.D.Search for more papers by this author, GERALD KLATSKIN, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-57-6-1018 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptDr. Joseph J. Bunim: The concurrence of psoriasis, sarcoidosis, and gout was first reported by Kaplan and Klatskin in 1960 (1). At the National Institutes of Health, Dr. Eugene Van Scott and his associates of the National Cancer Institute have been investigating the dermatologic and metabolic aspects of psoriasis; and for the past 2 years we at the National Institute of Arthritis and Metabolic Diseases have been collaborating with Dr. Van Scott in studying arthritis associated with psoriasis. Hyperuricemia commonly occurs in psoriasis, and the arthritis may superficially resemble gout. Nevertheless, we have observed a case of unequivocal gouty arthritis...References1. KAPLANKLATSKIN HG: Sarcoidosis, psoriasis, and gout: syndrome or coincidence? Yale J. Biol. Med. 32: 335, 1960. MedlineGoogle Scholar2. EISENSEEGMILLER AZJE: Uric acid metabolism in psoriasis. J. Clin. Invest. 40: 1486, 1961. CrossrefMedlineGoogle Scholar3. WRIGHT V: Rheumatism and psoriasis; a re-evaluation. Amer. J. Med. 27: 454, 1959. CrossrefMedlineGoogle Scholar4. SOKOLOFFBUNIM LJJ: Clinical and pathological studies of joint involvement in sarcoidosis. New Engl. J. Med. 260: 841, 1959. CrossrefMedlineGoogle Scholar5. KAPLAN H: Sarcoid arthritis with a response to colchicine; report of 2 cases. New Engl. J. Med. 263: 778, 1960. CrossrefMedlineGoogle Scholar6. GARRISON FH: History of Medicine, 4th Ed., W. B. Saunders Company, Philadelphia, 1929, p. 67. Google Scholar7. ROTHBERGCROUNSELEE SRGJL: Glycine-C14 incorporation into the proteins of normal stratum corneum and the abnormal stratum corneum of psoriasis. J. Invest. Derm. 37: 497, 1961. CrossrefMedlineGoogle Scholar8. VAN SCOTTREINERTSON EJRP: Morphologic and physiologic effects of chemotherapeutic agents in psoriasis. J. Invest. Derm. 33: 357, 1959. CrossrefMedlineGoogle Scholar9. KLATSKINYESNER GR: Hepatic manifestations of sarcoidosis and other granulomatous diseases; a study based on histological examination of tissue obtained by needle biopsy of the liver. Yale J. Biol. Med. 23: 207, 1950. MedlineGoogle Scholar10. SILTZBACH LE: The Kveim test in sarcoidosis; a study of 750 patients. JAMA 178: 476, 1961. CrossrefMedlineGoogle Scholar11. REICHLEWORK HSJL: Incidence and significance of healed miliary tubercles in the liver, spleen and kidneys. Arch. Path. 28: 331, 1939. Google Scholar12. HUTCHINSON J: (a) Anomalous disease of skin of fingers. (Papillary psoriasis?) Illustrations of Clinical Surgery, London, 1877, p. 42; (b) On eruptions which occur in connection with gout. Arch. Surg. 9: 315, 1898. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Bethesda, MarylandThis is an edited transcription of a combined clinical staff conference at the Clinical Center, Bethesda, Maryland, by the National Institute of Arthritis and Metabolic Diseases, National Institutes of Health, Public Health Service, Department of Health, Education, and Welfare.Requests for reprints should be addressed to Joseph J. Bunim, M.D., National Institute of Arthritis and Metabolic Diseases, Bethesda 14, Maryland. 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WEINBERGER, M.D., F.A.C.P.SarcoidosisSarcoidosis with ArthritisFurther Experience with Colchicine in the Treatment of Sarcoid Arthritis 1 December 1962Volume 57, Issue 6Page: 1018-1041KeywordsArthritisGoutInflammationMedical servicesMetabolic disordersPrevention, policy, and public healthPsoriasisPsoriatic arthritisSarcoidosisSpondylitis Issue Published: 1 December 1962 PDF DownloadLoading ...