Why the study?
How does surgical trauma affect thyroid hormone metabolism (TSH, T3, rT3, T4, T3-resin uptake)?
Population
30 women undergoing mastectomy (n=20) or cholecystectomy (n=10)
Design
Cohort
Follow-up
post-operative period
Authors
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May confound postoperative thyroid function test interpretation; leaves open effects on recovery and need for prospective trials.
How does surgical trauma affect thyroid hormone metabolism (TSH, T3, rT3, T4, T3-resin uptake)?
Surgical trauma induces significant and reciprocal changes in peripheral thyroid hormone metabolism, notably decreasing T3 and increasing rT3.
Adami et al. (1978) studied this question.
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