Chromosome analysis of solid tumors.I. Twenty-eight nonepithelial tumors

Of 25 nonepithelial solid cancers at least two appeared to have classically diploid stemlines. Of aneuploid tumors a few showed the same karyotype in every cell whereas other tumors showed unequivocal karyotype variation from cell to cell. One tumor contained a stemline marker apparently identical with one previously observed in Burkitt's lymphosarcoma. A number of tumors exhibited prominent secondary constriction patterns. Occasional cells showed broken chromosomes and multiradial forms. Two of three lymph nodes, diagnosed histologically as hyperplastic lymph nodes, showed classically diploid cells. A third showed unequivocal chromosome abnormalities.