Population
Adeno-associated virus (AAV) capsids (AAV1, AAV2, and AAV5 virions)
Design
Preclinical
Authors
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No immediate change to AAV vector protocols; leaves open validation of proteolytic mapping for capsid engineering in gene therapy.
Proteolytic mapping provides a novel approach for studying AAV capsid structure in solution, which is valuable for engineering AAV vectors for gene transfer.
Vliet et al. (2006) studied this question.
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