Why the study?
Does diabetic autonomic neuropathy impair the heart-rate response to sustained hand grip compared to normal subjects and diabetics without neuropathy?
Population
Normal subjects and diabetic subjects with and without proven autonomic neuropathy
Comparison
Sustained hand grip test vs Normal subjects vs. diabetic subjects without…
Design
Cross-sectional
Authors
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Early heart-rate response to hand grip may indicate parasympathetic neuropathy in diabetes; hypothesis-generating for autonomic testing.
Does diabetic autonomic neuropathy impair the heart-rate response to sustained hand grip compared to normal subjects and diabetics without neuropathy?
The early phase of heart-rate response to sustained hand grip is primarily mediated by parasympathetic withdrawal and is impaired in diabetic autonomic neuropathy.
Hume et al. (1979) studied this question.
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