Why the study?
Does radiotherapy combined with systemic chemotherapy (vincristine and cyclophosphamide) improve remission and survival in patients with localized Ewing's sarcoma?
Does radiotherapy combined with systemic chemotherapy (vincristine and cyclophosphamide) improve remission and survival in patients with localized Ewing's sarcoma?
Combination of radiotherapy and systemic chemotherapy with vincristine and cyclophosphamide leads to high rates of complete remission and extended survival in localized Ewing's sarcoma.
Answers are grounded in this paper and cite their sources.
May support combined radiotherapy-chemotherapy for localized Ewing sarcoma; leaves open need for randomized confirmation of durability.
Fifteen patients with localized Ewing's sarcoma were treated with 60Co teletherapy in doses of 5000 to 6500 rads and 1 to 2 years of systemic chemotherapy with vincristine and cyclophosphamide. All developed complete remissions of tumor, and 12 are surviving. Ten of the 12 have been continuously free of tumor since initial treatment for 91+, 84+, 67+, 31+, 21+, 19+, 17+, 12+, 11+, and 4+ months from diagnosis. The results suggest that this treatment is superior to other treatment methods with regard to extended tumor-free remission and survival.
No takes yet. Share an insight, caveat, or question.
Hustu et al. (1972) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: