Population
Cultured mouse and human myoblasts, human pulmonary A549 cells, dog myoblasts, and mice in vivo
Design
Preclinical
Authors
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May enhance muscle-targeted gene therapy delivery; hypothesis-generating from animal data and requires clinical validation before translation.
Glucocorticoid pretreatment enhances gene transfer efficiency into skeletal muscle cells in vitro and in vivo.
Braun et al. (1999) studied this question.
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