Role of angiotensin receptor blockers as monotherapy in reaching blood pressure goals
Why the study?
Does olmesartan medoxomil improve the attainment of combined SBP/DBP goals compared to other ARBs in hypertensive patients?
Population
Hypertensive patients
Comparison
Olmesartan medoxomil at recommended starting dose vs Losartan potassium, valsartan, or irbesartan at…
Design
Review
Authors
Discussion
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Member takes
Implication
May support olmesartan preference for BP goals; leaves open confirmation in randomized trials.
Structured PICO
Does olmesartan medoxomil improve the attainment of combined SBP/DBP goals compared to other ARBs in hypertensive patients?
P
Population
Hypertensive patients
I
Intervention
Olmesartan medoxomil at recommended starting dose
C
Comparator
Losartan potassium, valsartan, or irbesartan at recommended starting doses
O
Outcome
Attainment of combined SBP/DBP goal of <140/90 mm Hgsurrogate
Olmesartan medoxomil monotherapy at starting doses achieves higher rates of combined blood pressure goals compared to losartan, valsartan, or irbesartan in hypertensive patients.
Cite This Study
Oparil et al. (2005) studied this question.