This study provides the first evidence of species-specific differences in binding properties of pMCAT elements and identifies previously unrecognized beta MyHC proximal promoter elements contributing to non-weight-bearing regulation.
No takes yet. Share an insight, caveat, or question.
Species differences in pMCAT binding urge caution extrapolating rodent beta-MyHC data to humans; leaves open NWB regulatory mechanisms in human muscle.
Tsika et al. (2002) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: