Population
Myocytes freshly isolated from microdissected interlobar and arcuate arteries of rat kidney
Design
Preclinical
Authors
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Details ET-1 ion channel effects in rat renal vessels; extends mechanisms but leaves open human translation.
ET-1 signaling in rat renal microvascular smooth muscle cells involves a complex interplay of Ca2+, Cl-, and K+ channels that regulate membrane depolarization and intracellular calcium mobilization.
Gordienko et al. (1994) studied this question.
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