Why the study?
Does activation of β3-adrenoceptor promote rapid pacing-induced atrial electrical remodeling in rabbits?
Does activation of β3-adrenoceptor promote rapid pacing-induced atrial electrical remodeling in rabbits?
Activation of β3-adrenoceptors promotes atrial electrical remodeling and increases atrial fibrillation inducibility in a rabbit rapid pacing model, highlighting a potential pharmacological target.
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β3-AR activation promotes AF remodeling in rabbits; hypothesis-generating for antagonism as therapy with human trials needed.
Yu et al. (2011) studied this question.
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