Why the study?
Does enalaprilat prevent reflexive increases in cardiac interstitial norepinephrine compared to nicardipine during acute blood pressure lowering in spontaneously hypertensive rats?
Does enalaprilat prevent reflexive increases in cardiac interstitial norepinephrine compared to nicardipine during acute blood pressure lowering in spontaneously hypertensive rats?
Enalaprilat, unlike nicardipine, suppresses reflexive cardiac sympathetic activation during acute blood pressure lowering in a rat model.
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Enalaprilat may blunt reflexive cardiac sympathetic activation versus nicardipine in hypertensive rats; leaves open translation to human practice.
Calhoun et al. (2001) studied this question.
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