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May 1, 1970Journal of General Virology

Purification and Characterization of Bovine Enteroviruses

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Population

Three serologically distinct bovine enteroviruses (VG-5-27; vc-65-182; vp-7-19) grown in BHK21 cells

Design

Preclinical

Authors

SMSamuel MartinEuropean Bioinformatics InstituteMJM. JohnstonNational Institute of Environmental Health SciencesJCJ. Barklie ClementsInstitute of Virology of the Slovak Academy of Sciences

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Implication

Characterizes bovine enterovirus biophysics; leaves open roles in cattle disease and model utility for human enteroviruses.

Structured PICO

P
Population
Three serologically distinct bovine enteroviruses (VG-5-27; vc-65-182; vp-7-19) grown in BHK21 cells
I
Intervention
Purification procedure involving sedimentation and gel-filtration through a Sepharose 2B column
O
Outcome
Virus particle characteristics (shape, diameter, buoyant density, sedimentation coefficient, RNA characteristics)surrogate

The study successfully purified and characterized three bovine enteroviruses, detailing their physical and RNA properties.

Cite This Study

Martin et al. (1970) studied this question.

synapsesocial.com/papers/6a87cdf624ca9e5e63015b82https://doi.org/10.1099/0022-1317-7-2-103
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Selective Release of Proteins from a Bovine Enterovirus1972 · 9 citations
  2. 2Some comments concerning purification of bovine enterovirus.1985 · 3 citations
  3. 3A Possible Precursor containing RNA of a Bovine Enterovirus: the Provirion 111974 · 28 citations
  4. 4Capsid and Procapsid Proteins of a Bovine Enterovirus1971 · 24 citations
  5. 5The Complete Nucleotide Sequence of a Bovine Enterovirus1988 · 77 citations