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September 1, 1974Journal of General Virology

A Possible Precursor containing RNA of a Bovine Enterovirus: the Provirion 11

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Population

BHK 21 cells infected with bovine enterovirus (serotype VG-5-27)

Comparison

Purification and analysis of 145S particles vs 165S mature virus particles

Design

Preclinical

Authors

EHElizabeth M. HoeyQueen's University BelfastSMSamuel MartinEuropean Bioinformatics Institute

Discussion

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Implication

Identifies candidate provirion in bovine enterovirus; leaves open its conservation and functional role across picornaviruses.

Structured PICO

P
Population
BHK 21 cells infected with bovine enterovirus (serotype VG-5-27)
I
Intervention
Purification and analysis of 145S particles
C
Comparator
165S mature virus particles
O
Outcome
Polypeptide composition and RNA content of 145S particlessurrogate

The 145S particle of bovine enterovirus contains viral RNA and a distinct polypeptide composition, suggesting it acts as a provirion intermediate during viral maturation.

Cite This Study

Hoey et al. (1974) studied this question.

synapsesocial.com/papers/6a6f5764a528af2d65c2f184https://doi.org/10.1099/0022-1317-24-3-515
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Selective Release of Proteins from a Bovine Enterovirus1972 · 9 citations
  2. 2Capsid and Procapsid Proteins of a Bovine Enterovirus1971 · 24 citations
  3. 3Purification and Characterization of Bovine Enteroviruses1970 · 20 citations
  4. 4Evidence for Large Strands of Ribonucleic Acid Induced by a Bovine Enterovirus1971 · 18 citations
  5. 5Morphogenesis of Picornaviruses: Characterization and Assembly of Bovine Enterovirus Subviral Particles1976 · 22 citations