Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
April 23, 2012Archives of Internal MedicineOpen Access

Drug-Eluting vs Bare-Metal Stents in Primary Angioplasty

View Full Paper
Ask AI
Bookmark
Share

Why the study?

Do drug-eluting stents reduce target-vessel revascularization compared to bare-metal stents in patients undergoing primary percutaneous coronary intervention for STEMI?

Population

6,298 patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary…

Comparison

Drug-eluting stents vs Bare-metal stents (BMS)

Design

Meta-analysis

Follow-up

mean 1201 days (SD 440)

Authors

GLGiuseppe De LucaInterventional CardiologyMDMaurits T. DirksenNoordwest ZiekenhuisgroepCSChristian SpauldingInterventional / Structural Cardiology

Discussion

Loading...

Member takes

Overview

Supports DES over BMS to cut revascularization in STEMI PCI; confirms Level 1 meta-analytic evidence.

Structured PICO

Do drug-eluting stents reduce target-vessel revascularization compared to bare-metal stents in patients undergoing primary percutaneous coronary intervention for STEMI?

P
Population
6,298 patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention, pooled from 11 randomized trials
I
Intervention
Drug-eluting stents (99% sirolimus-eluting or paclitaxel-eluting stents)
C
Comparator
Bare-metal stents (BMS)
O
Outcome
Target-vessel revascularization at long-term follow-up (mean 1201 days)hard clinical

In patients with STEMI undergoing primary PCI, early-generation drug-eluting stents significantly reduce long-term target-vessel revascularization compared to bare-metal stents, though they carry an increased risk of very late stent thrombosis and reinfarction.

Cite This Study

Luca et al. (2012) studied this question.

synapsesocial.com/papers/6a87cf69f455bdf6826c8b6ehttps://doi.org/10.1001/archinternmed.2012.758
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Prasugrel versus Clopidogrel in Patients with Acute Coronary Syndromes2007 · 6,824 citations
  2. 2Is routine stenting for acute myocardial infarction superior to balloon angioplasty? A randomised comparison in a large cohort of unselected patients2005 · 70 citations
  3. 3Ticagrelor versus Clopidogrel in Patients with Acute Coronary Syndromes2009 · 7,158 citations