Clinical Outcome After Primary Percutaneous Coronary Intervention With Drug-Eluting and Bare Metal Stents in Patients With ST-Segment Elevation Myocardial Infarction
Why the study?
Does the use of drug-eluting stents compared to bare metal stents improve clinical outcomes in patients with ST-segment elevation myocardial infarction undergoing primary PCI?
Population
3756 consecutive patients with ST-segment elevation myocardial infarction treated with primary percutaneous…
Comparison
Drug-eluting stents (DES) vs Bare metal stents (BMS)
Design
Cohort
Follow-up
2 years
Authors
Discussion
Loading...
Member takes
Implication
Caution advised with DES in STEMI primary PCI; observational data leaves net benefit unresolved.
Structured PICO
Does the use of drug-eluting stents compared to bare metal stents improve clinical outcomes in patients with ST-segment elevation myocardial infarction undergoing primary PCI?
P
Population
3756 consecutive patients with ST-segment elevation myocardial infarction treated with primary percutaneous coronary intervention (PCI) and stent implantation
I
Intervention
Drug-eluting stents (DES)
C
Comparator
Bare metal stents (BMS)
O
Outcome
Target lesion revascularization (TLR), stent thrombosis, myocardial infarction, and death at 2 yearshard clinical
In STEMI patients undergoing primary PCI, DES reduces target lesion revascularization compared to BMS but is associated with a higher risk of very late stent thrombosis.
Cite This Study
Jensen et al. (2008) studied this question.