What question did this study set out to answer?

Evaluate the bio-efficacy of conventional pyrethroid-only nets compared to combination pyrethroid and piperonyl butoxide (PBO) nets against multi-insecticide resistant Anopheles mosquitoes.

June 13, 2018Wellcome Open ResearchOpen Access

Experimental huts trial of the efficacy of pyrethroids/piperonyl butoxide (PBO) net treatments for controlling multi-resistant populations of Anopheles funestus s.s. in Kpomè, Southern Benin

View Full Paper

Ask AI

Bookmark

Authors

RARomaric AkotonUniversité d'Abomey-Calavi GTGeneviève TchigossouUniversité d'Abomey-Calavi IDInnocent DjègbéÉcole Normale Supérieure

Discussion

Member takes

Implication

Experimental trial demonstrates superior vector mortality with pyrethroid-PBO nets in resistant Anopheles populations, indicating the value of next-generation bed nets for malaria control.

Key Points

Evaluate the bio-efficacy of conventional pyrethroid-only nets compared to combination pyrethroid and piperonyl butoxide (PBO) nets against multi-insecticide resistant Anopheles mosquitoes.
Assessed net bio-efficacy against Anopheles funestus and Anopheles gambiae using World Health Organization (WHO) cone and tunnel tests in Kpomè, Southern Benin.
Conducted a release-recapture experimental hut trial following WHO guidelines to compare conventional pyrethroid-only LLINs against pyrethroid-PBO combination nets.
Quantified baseline insecticide and PBO residue concentrations on the test nets prior to hut trials using high performance liquid chromatography (HPLC).
Pyrethroid-PBO combination nets (Types 1 and 3) significantly increased mosquito mortality compared to conventional pyrethroid-only nets (Types 2 and 4) against local resistant mosquito populations (P < 0.0001).
Tunnel tests against Anopheles funestus s.s. demonstrated mortality exceeding 80% for pyrethroid-PBO nets, compared to 65.53 ± 8.33% for Type 2 and 71.25 ± 7.92% for Type 4 conventional nets.
Evaluation against local multi-resistant Anopheles coluzzii populations achieved mortality rates ranging between 77% and 87% with pyrethroid-PBO nets.

Cite This Study

Akoton et al. (2018) studied this question.

synapsesocial.com/papers/6a87cf8a4f54442d18262f89 https://doi.org/10.12688/wellcomeopenres.14589.1

View Full Paper

Ask AI

Bookmark

Implication

Experimental trial demonstrates superior vector mortality with pyrethroid-PBO nets in resistant Anopheles populations, indicating the value of next-generation bed nets for malaria control.

Experimental huts trial of the efficacy of pyrethroids/piperonyl butoxide (PBO) net treatments for controlling multi-resistant populations of Anopheles funestus s.s. in Kpomè, Southern Benin

Discussion

Member takes

Implication

Key Points

Cite This Study

Experimental huts trial of the efficacy of pyrethroids/piperonyl butoxide (PBO) net treatments for controlling multi-resistant populations of Anopheles funestus s.s. in Kpomè, Southern Benin

Discussion

Member takes

Implication

Key Points

Cite This Study

Also Consider

Also Consider