A new series of 1-sulfonly substituted imidazole compounds (containing 19 compounds) were synthesized and characterized by 1 HNMR, 13 CNMR and HRMS. 2d, 2e, 2h, 2i showed promising activities in animal test (in rats) for anti-inflammation. 2k - 2t were used in Chemokine Receptors CXCR4 receptor agonist Calcium assay showed no activities.
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Ren et al. (2011) studied this question.
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