Why the study?
Pre-procedural planning is paramount to avoiding LVOT obstruction, a prevalent and potentially lethal complication of TMVR.
A novel framework utilizing 3-D imaging, in silico modeling, and virtual reality is proposed to improve pre-procedural planning and predict LVOT obstruction in transcatheter mitral valve replacement.
May aid TMVR planning; leaves open clinical impact on LVOT obstruction pending validation.
Transcatheter mitral valve replacement (TMVR) is an emerging therapy for patients with severe mitral valve disease considered unsuitable for conventional surgery. Pre-procedural planning is paramount to avoiding left ventricular outflow tract (LVOT) obstruction, a prevalent and potentially lethal complication of TMVR. The current method to predict LVOT obstruction involves estimating the cross-sectional area of the elongated LVOT after TMVR (i.e. neo-LVOT) using computed tomography (CT) by overlaying a virtual device onto the anatomy in a single phase of the cardiac cycle.
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Kohli et al. (2020) studied this question.
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