Key result
A predicted neoLVOT of <190 mm2 using 3D computer-aided design models portends a high risk of left ventricular outflow tract obstruction following transcatheter mitral valve replacement.
Why the study?
Does a predicted neoLVOT of <190 mm2 using 3-D computer-aided design models predict LVOT obstruction following transcatheter mitral valve replacement?
Does a predicted neoLVOT of <190 mm2 using 3-D computer-aided design models predict LVOT obstruction following transcatheter mitral valve replacement?
A predicted neoLVOT of <190 mm2 using 3D modeling indicates a high risk of fatal LVOT obstruction after TMVR, though current models have notable anatomical and physiological limitations.
Key Points TMVR can cause fatal LVOT obstruction, especially in the setting of valve‐in‐mitral annular calcification. A predicted neoLVOT of <190 mm2, measured using computer aided design models of 3‐D datasets with a virtual valve implant, portends a high risk of LVOT obstruction following TMVR. NeoLVOT predictions may be based on different valve implantation depths, and do not account for body mass, complex neoLVOT time‐varying three‐dimensional geometry, flow, or anterior mitral leaflet dynamics.
No takes yet. Share an insight, caveat, or question.
Khan et al. (2018) conducted an editorial in Left ventricular outflow tract obstruction following transcatheter mitral valve replacement. Predicted neoLVOT <190 mm2 was evaluated on LVOT obstruction following TMVR. A predicted neoLVOT of <190 mm2 using 3D computer-aided design models portends a high risk of left ventricular outflow tract obstruction following transcatheter mitral valve replacement.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: