Why the study?
Does the type of initial poliomyelitis case (paralytic vs nonparalytic) affect the risk of subsequent paralytic cases among household contacts in nonepidemic years?
Does the type of initial poliomyelitis case (paralytic vs nonparalytic) affect the risk of subsequent paralytic cases among household contacts in nonepidemic years?
This study investigates whether the type of initial poliomyelitis case in a household predicts the type of subsequent cases among contacts during nonepidemic years.
Should not change household contact management for polio; leaves open whether initial case type predicts paralytic risk among contacts.
A RECENT study on multiple household cases of poliomyelitis revealed a significant relation between the type of disease observed in the first member to be affected and the subsequent occurrence of clinical infection among other persons in the family.1 It was found that the probability that subsequent cases in the family would be paralytic was greater when the initial case was paralytic than when it was nonparalytic.The results obtained under epidemic conditions prevailing in the 1949 outbreak posed the question of whether a similar phenomenon occurred in nonepidemic years. Accordingly, the available data on household members in families having . . .
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Siegel et al. (1955) studied this question.
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