This review highlights recent advances in understanding the genetic architecture of atrial fibrillation and discusses the potential future implications for clinical management.
Expanding genetic insights into AF supports ongoing research; leaves open translation to clinical management.
Atrial fibrillation (AF) is an arrhythmia with a genetic basis. Over the past decade, rapid advances in genotyping technology have revolutionised research regarding the genetic basis of AF. While AF genetics research was previously largely restricted to familial forms of AF, recent studies have begun to characterise the genetic architecture underlying the form of AF encountered in everyday clinical practice. These discoveries could have a significant impact on the management of AF. However, much work remains before genetic findings can be translated to clinical practice. This review summarises results of studies in AF genetics to date and discusses the potential implications of these findings in clinical practice.
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Saagar Mahida (2014) studied this question.
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